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CpG oligodeoxynucleotides enhance chemosensitivity of 5-fluorouracil in HepG2 human hepatoma cells via downregulation of the antiapoptotic factors survivin and livin

BACKGROUND: Recent studies indicated that a synthetic oligonucleotide containing un-methylated CpG oligodeoxynucleotides (CpG-ODN) has a potential function for cancer therapy. In this study, we evaluated the chemosensitizing effects of CpG-ODN in 5-fluorouracil (5-FU)-treated HepG2 human hepatoma ce...

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Detalles Bibliográficos
Autores principales:	Liang, Sheng-ran, Hu, Guang-rui, Fang, Li-juan, Huang, Su-jing, Li, Jin-song, Zhao, Ming-yi, Meng, Min-jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176997/ https://www.ncbi.nlm.nih.gov/pubmed/24161202 http://dx.doi.org/10.1186/1475-2867-13-106

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