Protein kinase RNA- like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)- mediated endoplasmic reticulum stress- induced apoptosis in diabetic cardiomyopathy

BACKGROUND: Endoplasmic reticulum (ER) stress is considered one of the mechanisms contributing to reactive oxygen species (ROS)- mediated cell apoptosis. In diabetic cardiomyopathy (DCM), cell apoptosis is generally accepted as the etiological factor and closely related to cardiac ROS generation. ER...

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Detalles Bibliográficos
Autores principales: Liu, Zhong-Wei, Zhu, Hai-Tao, Chen, Kun-Lun, Dong, Xin, Wei, Jin, Qiu, Chuan, Xue, Jia-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176998/
https://www.ncbi.nlm.nih.gov/pubmed/24180212
http://dx.doi.org/10.1186/1475-2840-12-158

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