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Antifungal drug resistance evokedvia RNAi-dependent epimutations

Microorganisms evolve via mechanisms spanning sexual/parasexual reproduction, mutators, aneuploidy, Hsp90, and even prions. Mechanisms that may seem detrimental can be repurposed to generate diversity. Here we show the human fungal pathogen Mucor circinelloides develops spontaneous resistance to the...

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Detalles Bibliográficos
Autores principales:	Calo, Silvia, Shertz-Wall, Cecelia, Lee, Soo Chan, Bastidas, Robert J., Nicolás, Francisco E., Granek, Joshua A., Mieczkowski, Piotr, Torres-Martinez, Santiago, Ruiz-Vazquez, Rosa M., Cardenas, Maria E., Heitman, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177005/ https://www.ncbi.nlm.nih.gov/pubmed/25079329 http://dx.doi.org/10.1038/nature13575

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