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A mouse line for inducible and reversible silencing of specific neurons

BACKGROUND: Genetic methods for inducibly and reversibly inhibiting neuronal activity of specific neurons are critical for exploring the functions of neuronal circuits. The engineered human glycine receptor, called ivermectin (IVM)-gated silencing receptor (IVMR), has been shown to possess this abil...

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Detalles Bibliográficos
Autores principales: Hu, Ling, Lan, Wei, Guo, Hao, Chai, Guo-Dong, Huang, Kun, Zhang, Ling, Huang, Ying, Chen, Xue-Feng, Zhang, Lei, Song, Ning-Ning, Chen, Ling, Lang, Bing, Wang, Yun, Wang, Qing-Xiu, Zhang, Jin-Bao, McCaig, Collin, Xu, Lin, Ding, Yu-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177062/
https://www.ncbi.nlm.nih.gov/pubmed/25231486
http://dx.doi.org/10.1186/s13041-014-0068-8