Influence of pH control in the formation of inclusion bodies during production of recombinant sphingomyelinase-D in Escherichia coli

BACKGROUND: Inclusion bodies (IBs) are aggregated proteins that form clusters when protein is overexpressed in heterologous expression systems. IBs have been considered as non-usable proteins, but recently they are being used as functional materials, catalytic particles, drug delivery agents, immuno...

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Detalles Bibliográficos
Autores principales: Castellanos-Mendoza, Andrea, Castro-Acosta, Ricardo M, Olvera, Alejandro, Zavala, Guadalupe, Mendoza-Vera, Miguel, García-Hernández, Enrique, Alagón, Alejandro, Trujillo-Roldán, Mauricio A, Valdez-Cruz, Norma A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177172/
https://www.ncbi.nlm.nih.gov/pubmed/25213001
http://dx.doi.org/10.1186/s12934-014-0137-9

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