Cargando…

Selected Aspects of Molecular Diagnostics of Constitutional Alterations in BRCA1 and BRCA2 Genes Associated with Increased Risk of Breast Cancer in the Polish Population

OBJECTIVES: This study was undertaken to determine: 1) Type and prevalence of founder mutations BRCA1 and BRCA2 genes in Polish families with strong aggregation of breast and/or ovarian cancer. 2) Risk of breast and/or ovarian cancer depending on type of BRCA1 gene mutation. 3) Prevalence of BRCA1 m...

Descripción completa

Detalles Bibliográficos
Autor principal:	Górski, Bohdan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177211/ https://www.ncbi.nlm.nih.gov/pubmed/20223018 http://dx.doi.org/10.1186/1897-4287-4-3-142

Ejemplares similares

Large genomic rearrangements in BRCA1 and BRCA2 genes in breast and ovarian cancer families in Poland
por: Bielecka, Helena, et al.
Publicado: (2012)

Large genomic rearrangements in BRCA1 and BRCA2 genes in breast and ovarian cancer families in Poland
por: Bielecka, Helena, et al.
Publicado: (2012)

BRCA1 testing
por: Górski, Bohdan, et al.
Publicado: (2008)

BRCA1/2 mutations are not a common cause of malignant melanoma in the Polish population
por: Dębniak, Tadeusz, et al.
Publicado: (2018)

Germline Mutations in BRCA1 and BRCA2 in Polish Families Predisposed to Breast and Ovary Cancers
por: Grzybowska, E., et al.
Publicado: (1999)

A common missense variant in BRCA2 predisposes to early onset breast cancer
por: Górski, Bohdan, et al.
Publicado: (2005)

Prevalence of the most frequent BRCA1 mutations in Polish population
por: Brozek, Izabela, et al.
Publicado: (2011)

Ovarian cancer risk in Polish BRCA1 mutation carriers is not associated with the prohibitin 3' untranslated region polymorphism
por: Jakubowska, Anna, et al.
Publicado: (2008)

Constitutional alterations of 9p23-24 in independent BRCA2 breast cancer families
por: Schwab, M, et al.
Publicado: (2000)

The occurrence of germline BRCA1 and BRCA2 sequence alterations in Slovenian population
por: Stegel, Vida, et al.
Publicado: (2011)

BRCA1 founder mutations do not contribute to increased risk of gastric cancer in the Polish population
por: Ławniczak, Małgorzata, et al.
Publicado: (2016)

Are BRCA1- and BRCA2-related breast cancers associated with increased mortality?
por: Gareth Evans, D, et al.
Publicado: (2004)

Selected aspects of genetic counselling for BRCA1 mutation carriers
por: Gronwald, Jacek
Publicado: (2007)

Contribution of germline BRCA1 and BRCA2 sequence alterations to breast cancer in Northern India
por: Saxena, Sunita, et al.
Publicado: (2006)

BRCA1 founder mutations and beyond in the Polish population: A single-institution BRCA1/2 next-generation sequencing study
por: Kowalik, Artur, et al.
Publicado: (2018)

Molecular Trajectory of BRCA1 and BRCA2 Mutations
por: Hatano, Yuichiro, et al.
Publicado: (2020)

BRCA1 and BRCA2 mutations in a population-based study of male breast cancer
por: Basham, Victoria M, et al.
Publicado: (2002)

Resveratrol increases BRCA1 and BRCA2 mRNA expression in breast tumour cell lines
por: Fustier, P, et al.
Publicado: (2003)

BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2
por: Cline, Melissa S., et al.
Publicado: (2018)

Molecular analysis of the BRCA1 and BRCA2 genes in 32 breast and/or ovarian cancer Spanish families
por: Osorio, A, et al.
Publicado: (2000)

Comprehensive molecular comparison of BRCA1 hypermethylated and BRCA1 mutated triple negative breast cancers
por: Glodzik, Dominik, et al.
Publicado: (2020)

Clinical outcome of breast cancer in carriers of BRCA1 and BRCA2 mutations according to molecular subtypes
por: Talhouet, Solene De, et al.
Publicado: (2020)

Screening BRCA1 and BRCA2 Mutation Carriers for Breast Cancer
por: Warner, Ellen
Publicado: (2018)

BRCA1 and BRCA2 germline mutation analysis in the Indonesian population
por: Purnomosari, Dewajani, et al.
Publicado: (2007)

Prognostic factors in Polish patients with BRCA1-dependent ovarian cancer
por: Szatkowski, Wiktor, et al.
Publicado: (2016)

Constitutional mosaicism for a BRCA2 mutation as a cause of early-onset breast cancer
por: Alhopuro, Pia, et al.
Publicado: (2020)

Consistency of BRCA1 and BRCA2 Variant Classifications Among Clinical Diagnostic Laboratories
por: Lincoln, Stephen E., et al.
Publicado: (2017)

Phase 1 trial of olaparib and oral cyclophosphamide in BRCA breast cancer, recurrent BRCA ovarian cancer, non-BRCA triple-negative breast cancer, and non-BRCA ovarian cancer
por: Lee, Chee Khoon, et al.
Publicado: (2019)

Predominance of BRCA2 Mutation and Estrogen Receptor Positivity in Unselected Breast Cancer with BRCA1 or BRCA2 Mutation
por: Pujol, Pascal, et al.
Publicado: (2022)

Molecular contribution of BRCA1 and BRCA2 to genome instability in breast cancer patients: review of radiosensitivity assays
por: Sadeghi, Fatemeh, et al.
Publicado: (2020)

Recurrent Mutations in BRCA1, BRCA2, RAD51C, PALB2 and CHEK2 in Polish Patients with Ovarian Cancer
por: Łukomska, Alicja, et al.
Publicado: (2021)

Mutations of the BRCA1 and BRCA2 genes in patients with bilateral breast cancer
por: Steinmann, D, et al.
Publicado: (2001)

Variation in breast cancer risk in BRCA1 and BRCA2 mutation carriers
por: Rebbeck, Timothy R, et al.
Publicado: (2008)

Breast cancer prevention in women with a BRCA1 or BRCA2 mutation
por: Metcalfe, Kelly A, et al.
Publicado: (2007)

Risks of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers
por: Ahmed, M, et al.
Publicado: (2010)

Predictors of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers
por: Metcalfe, K, et al.
Publicado: (2011)

Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers
por: Kotsopoulos, Joanne, et al.
Publicado: (2012)

Prevalence of BRCA1 and BRCA2 Mutations in Korean Breast Cancer Patients
por: Ahn, Sei Hyun, et al.
Publicado: (2004)

Distribution of BRCA1 and BRCA2 Mutations in Asian Patients with Breast Cancer
por: Kim, Haeyoung, et al.
Publicado: (2013)

The importance of BRCA1 and BRCA2 genes mutations in breast cancer development
por: Mehrgou, Amir, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_974ripc1fenk2jbn1cju2ggbin