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A-770041 reverses paclitaxel and doxorubicin resistance in osteosarcoma cells

BACKGROUND: Reversing multidrug resistance (MDR) has been an important goal for clinical and investigational oncologists. In the last few decades, significant effort has been made to search for inhibitors to reverse MDR by targeting ATP-binding cassette (ABC) transporters (Pgp, MRP) directly, but th...

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Detalles Bibliográficos
Autores principales: Duan, Zhenfeng, Zhang, Jianming, Ye, Shunan, Shen, Jacson, Choy, Edwin, Cote, Gregory, Harmon, David, Mankin, Henry, Hua, Yingqi, Zhang, Yu, Gray, Nathanael S, Hornicek, Francis J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177239/
https://www.ncbi.nlm.nih.gov/pubmed/25236161
http://dx.doi.org/10.1186/1471-2407-14-681