High-frequency aberrantly methylated targets in pancreatic adenocarcinoma identified via global DNA methylation analysis using methylCap-seq

BACKGROUND: Extensive reprogramming and dysregulation of DNA methylation is an important characteristic of pancreatic cancer (PC). Our study aimed to characterize the genomic methylation patterns in various genomic contexts of PC. The methyl capture sequencing (methylCap-seq) method was used to map...

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Detalles Bibliográficos
Autores principales: Zhao, Yangxing, Sun, Jinfeng, Zhang, Hongyu, Guo, Shicheng, Gu, Jun, Wang, Wei, Tang, Ning, Zhou, Xiaoyu, Yu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177372/
https://www.ncbi.nlm.nih.gov/pubmed/25276247
http://dx.doi.org/10.1186/1868-7083-6-18

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