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Deletion of Serum Amyloid A3 Improves High Fat High Sucrose Diet-Induced Adipose Tissue Inflammation and Hyperlipidemia in Female Mice
Serum amyloid A (SAA) increases in response to acute inflammatory stimuli and is modestly and chronically elevated in obesity. SAA3, an inducible form of SAA, is highly expressed in adipose tissue in obese mice where it promotes monocyte chemotaxis, providing a mechanism for the macrophage accumulat...
Autores principales: | den Hartigh, Laura J., Wang, Shari, Goodspeed, Leela, Ding, Yilei, Averill, Michelle, Subramanian, Savitha, Wietecha, Tomasz, O'Brien, Kevin D., Chait, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177399/ https://www.ncbi.nlm.nih.gov/pubmed/25251243 http://dx.doi.org/10.1371/journal.pone.0108564 |
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