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Genome-wide binding of the basic helix-loop-helix myogenic inhibitor musculin has substantial overlap with MyoD: implications for buffering activity

BACKGROUND: Musculin (MSC) is a basic helix-loop-helix transcription factor that inhibits myogenesis during normal development and contributes to the differentiation defect in rhabdomyosarcoma. As one of many transcription factors that impede myogenesis, its binding on a genome-wide scale relative t...

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Detalles Bibliográficos
Autores principales: MacQuarrie, Kyle L, Yao, Zizhen, Fong, Abraham P, Tapscott, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177542/
https://www.ncbi.nlm.nih.gov/pubmed/24175993
http://dx.doi.org/10.1186/2044-5040-3-26