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Clinical development of phosphatidylinositol 3-kinase inhibitors for non-Hodgkin lymphoma
Phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling pathway is extensively explored in cancers. It functions as an important regulator of cell growth, survival and metabolism. Activation of this pathway also predicts poor prognosis in numerous human malignancies....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177547/ https://www.ncbi.nlm.nih.gov/pubmed/24252186 http://dx.doi.org/10.1186/2050-7771-1-30 |