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Xanthene Derivatives Increase Glucose Utilization through Activation of LKB1-Dependent AMP-Activated Protein Kinase
5′ AMP-activated protein kinase (AMPK) is a highly conserved serine-threonine kinase that regulates energy expenditure by activating catabolic metabolism and suppressing anabolic pathways to increase cellular energy levels. Therefore AMPK activators are considered to be drug targets for treatment of...
Autores principales: | Kwon, Yonghoon, Song, Parkyong, Yoon, Jong Hyuk, Ghim, Jaewang, Kim, Dayea, Kang, Byungjun, Lee, Taehoon G., Kim, Jin-Ah, Choi, Joong-Kwon, Youn, In Kwon, Lee, Hyeon-Kyu, Ryu, Sung Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177559/ https://www.ncbi.nlm.nih.gov/pubmed/25250787 http://dx.doi.org/10.1371/journal.pone.0108771 |
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