Polymorphisms of Toll-like receptor-4 and CD14 in systemic lupus erythematosus and rheumatoid arthritis

BACKGROUND: Toll-like receptor 4 (TLR4) and its co-receptor CD14 play a major role in innate immunity by recognizing PAMPs and signal the activation of adaptive responses. These receptors can recognize endogenous ligands mainly auto-antigens. In addition, TLR4 (Asp299Gly) and CD14 (C/T -159) polymor...

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Detalles Bibliográficos
Autores principales: Dhaouadi, Tarak, Sfar, Imen, Haouami, Youssra, Abdelmoula, Leila, Turki, Sami, Hassine, Lamia Ben, Zouari, Rafik, Khedher, Adel, Khalfallah, Narjess, Abdallah, Taieb Ben, Gorgi, Yousr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177616/
https://www.ncbi.nlm.nih.gov/pubmed/24252506
http://dx.doi.org/10.1186/2050-7771-1-20

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