A case of pediatric B-Lymphoblastic leukemia presenting with a t(9;12)(p24;q11.2) involving JAK2 and concomitant MLL rearrangement with apparent insertion at 6q27

BACKGROUND: B-cell acute lymphoblastic leukemia (B-ALL) is the most common malignancy in pediatric patients and the leading cause of cancer-related death in children and young adults. Translocations of 9p24 involving JAK2 (9p24) and gain-of-function mutations of JAK2 with subsequent activation of th...

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Detalles Bibliográficos
Autores principales: Tirado, Carlos A, Shabsovich, David, DeNicola, Matthew, Rao, Dinesh, Yang, Lynn, Garcia, Rolando, Rao, Nagesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177618/
https://www.ncbi.nlm.nih.gov/pubmed/24274401
http://dx.doi.org/10.1186/2050-7771-1-31

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