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Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam

Achillea tenuifolia Lam. (Asteraceae) afforded a methanolic extract from which after fractionation in solvents with different polarities, two known flavones 3’, 5- dihydroxy- 4’, 6, 7- trimethoxy flavone (eupatorine, compound 3), 5- hydroxy- 3’,4’, 6, 7- tetramethoxyflavone (compound 4), besides ste...

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Autores principales: Moradkhani, Shirin, Kobarfard, Farzad, Ayatollahi, Seyed Abdol Majid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177627/
https://www.ncbi.nlm.nih.gov/pubmed/25276207
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author Moradkhani, Shirin
Kobarfard, Farzad
Ayatollahi, Seyed Abdol Majid
author_facet Moradkhani, Shirin
Kobarfard, Farzad
Ayatollahi, Seyed Abdol Majid
author_sort Moradkhani, Shirin
collection PubMed
description Achillea tenuifolia Lam. (Asteraceae) afforded a methanolic extract from which after fractionation in solvents with different polarities, two known flavones 3’, 5- dihydroxy- 4’, 6, 7- trimethoxy flavone (eupatorine, compound 3), 5- hydroxy- 3’,4’, 6, 7- tetramethoxyflavone (compound 4), besides stearic acid (compound 1), lupeol (compound 2), daucosterol (β- sitosterol 3-O- β- D- glucopyranoside, compound 5), 2, 4- dihydroxy methyl benzoate (compound 6) were isolated for the first time. The structure of isolated compounds was elucidated by means of different spectroscopic methods such as UV, IR, Mass and 1H- NMR (1D and 2D) and 13C-NMR. For further confirming the structures of isolated compounds, comparison of the spectral data of them with those reported in the litratures have been done.
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spelling pubmed-41776272014-09-30 Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam Moradkhani, Shirin Kobarfard, Farzad Ayatollahi, Seyed Abdol Majid Iran J Pharm Res Original Article Achillea tenuifolia Lam. (Asteraceae) afforded a methanolic extract from which after fractionation in solvents with different polarities, two known flavones 3’, 5- dihydroxy- 4’, 6, 7- trimethoxy flavone (eupatorine, compound 3), 5- hydroxy- 3’,4’, 6, 7- tetramethoxyflavone (compound 4), besides stearic acid (compound 1), lupeol (compound 2), daucosterol (β- sitosterol 3-O- β- D- glucopyranoside, compound 5), 2, 4- dihydroxy methyl benzoate (compound 6) were isolated for the first time. The structure of isolated compounds was elucidated by means of different spectroscopic methods such as UV, IR, Mass and 1H- NMR (1D and 2D) and 13C-NMR. For further confirming the structures of isolated compounds, comparison of the spectral data of them with those reported in the litratures have been done. Shaheed Beheshti University of Medical Sciences 2014 /pmc/articles/PMC4177627/ /pubmed/25276207 Text en © 2014 by School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Moradkhani, Shirin
Kobarfard, Farzad
Ayatollahi, Seyed Abdol Majid
Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam
title Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam
title_full Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam
title_fullStr Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam
title_full_unstemmed Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam
title_short Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam
title_sort phytochemical investigations on chemical constituents of achillea tenuifolia lam
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177627/
https://www.ncbi.nlm.nih.gov/pubmed/25276207
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