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Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam
Achillea tenuifolia Lam. (Asteraceae) afforded a methanolic extract from which after fractionation in solvents with different polarities, two known flavones 3’, 5- dihydroxy- 4’, 6, 7- trimethoxy flavone (eupatorine, compound 3), 5- hydroxy- 3’,4’, 6, 7- tetramethoxyflavone (compound 4), besides ste...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Shaheed Beheshti University of Medical Sciences
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177627/ https://www.ncbi.nlm.nih.gov/pubmed/25276207 |
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author | Moradkhani, Shirin Kobarfard, Farzad Ayatollahi, Seyed Abdol Majid |
author_facet | Moradkhani, Shirin Kobarfard, Farzad Ayatollahi, Seyed Abdol Majid |
author_sort | Moradkhani, Shirin |
collection | PubMed |
description | Achillea tenuifolia Lam. (Asteraceae) afforded a methanolic extract from which after fractionation in solvents with different polarities, two known flavones 3’, 5- dihydroxy- 4’, 6, 7- trimethoxy flavone (eupatorine, compound 3), 5- hydroxy- 3’,4’, 6, 7- tetramethoxyflavone (compound 4), besides stearic acid (compound 1), lupeol (compound 2), daucosterol (β- sitosterol 3-O- β- D- glucopyranoside, compound 5), 2, 4- dihydroxy methyl benzoate (compound 6) were isolated for the first time. The structure of isolated compounds was elucidated by means of different spectroscopic methods such as UV, IR, Mass and 1H- NMR (1D and 2D) and 13C-NMR. For further confirming the structures of isolated compounds, comparison of the spectral data of them with those reported in the litratures have been done. |
format | Online Article Text |
id | pubmed-4177627 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Shaheed Beheshti University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-41776272014-09-30 Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam Moradkhani, Shirin Kobarfard, Farzad Ayatollahi, Seyed Abdol Majid Iran J Pharm Res Original Article Achillea tenuifolia Lam. (Asteraceae) afforded a methanolic extract from which after fractionation in solvents with different polarities, two known flavones 3’, 5- dihydroxy- 4’, 6, 7- trimethoxy flavone (eupatorine, compound 3), 5- hydroxy- 3’,4’, 6, 7- tetramethoxyflavone (compound 4), besides stearic acid (compound 1), lupeol (compound 2), daucosterol (β- sitosterol 3-O- β- D- glucopyranoside, compound 5), 2, 4- dihydroxy methyl benzoate (compound 6) were isolated for the first time. The structure of isolated compounds was elucidated by means of different spectroscopic methods such as UV, IR, Mass and 1H- NMR (1D and 2D) and 13C-NMR. For further confirming the structures of isolated compounds, comparison of the spectral data of them with those reported in the litratures have been done. Shaheed Beheshti University of Medical Sciences 2014 /pmc/articles/PMC4177627/ /pubmed/25276207 Text en © 2014 by School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Moradkhani, Shirin Kobarfard, Farzad Ayatollahi, Seyed Abdol Majid Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam |
title | Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam |
title_full | Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam |
title_fullStr | Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam |
title_full_unstemmed | Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam |
title_short | Phytochemical Investigations on Chemical Constituents of Achillea tenuifolia Lam |
title_sort | phytochemical investigations on chemical constituents of achillea tenuifolia lam |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177627/ https://www.ncbi.nlm.nih.gov/pubmed/25276207 |
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