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Antimicrobial and Antioxidant Activities of Bauhinia racemosa Lam. and Chemical Content

Methanol 70% extract of Bauhinia racemosa aerial parts was tested for antimicrobial activity against different bacterial and fungal strains and for antioxidant activity and also total content of polyphenols with phytochemical analysis of the extract was determined. The results have showed that the e...

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Autores principales: Rashed, Khaled, Butnariu, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177630/
https://www.ncbi.nlm.nih.gov/pubmed/25276210
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author Rashed, Khaled
Butnariu, Monica
author_facet Rashed, Khaled
Butnariu, Monica
author_sort Rashed, Khaled
collection PubMed
description Methanol 70% extract of Bauhinia racemosa aerial parts was tested for antimicrobial activity against different bacterial and fungal strains and for antioxidant activity and also total content of polyphenols with phytochemical analysis of the extract was determined. The results have showed that the extract has a significant antimicrobial activity, it inhibited the growth of Bacillus subtilis and also it was highly active against Candida albicans suggesting that it can be used in the treatment of fungal infections. The extract has a good antioxidant activity, it has shown high values of the trolox equivalent antioxidant capacity and polyphenol content while it has shown a lower value of oxygen radical absorbance capacity. Phytochemical analysis has shown that it has interesting phytochemical bioconstituents, include flavonoids, tannins and others, and the deep phytochemical study results in the isolation of methyl gallate, gallic, kaempferol, quercetin, querection 3–O–α–rhamnoside, kaempferol 3–O–β–glucoside, myricetin–3–O–β– glucoside, querection–3–O–rutinoside (Rutin). All compounds were identified by different spectroscopic analyses (UV, (1)H–NMR, (13)C–NMR) and Mass Spectrometry (MS).
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spelling pubmed-41776302014-09-30 Antimicrobial and Antioxidant Activities of Bauhinia racemosa Lam. and Chemical Content Rashed, Khaled Butnariu, Monica Iran J Pharm Res Original Article Methanol 70% extract of Bauhinia racemosa aerial parts was tested for antimicrobial activity against different bacterial and fungal strains and for antioxidant activity and also total content of polyphenols with phytochemical analysis of the extract was determined. The results have showed that the extract has a significant antimicrobial activity, it inhibited the growth of Bacillus subtilis and also it was highly active against Candida albicans suggesting that it can be used in the treatment of fungal infections. The extract has a good antioxidant activity, it has shown high values of the trolox equivalent antioxidant capacity and polyphenol content while it has shown a lower value of oxygen radical absorbance capacity. Phytochemical analysis has shown that it has interesting phytochemical bioconstituents, include flavonoids, tannins and others, and the deep phytochemical study results in the isolation of methyl gallate, gallic, kaempferol, quercetin, querection 3–O–α–rhamnoside, kaempferol 3–O–β–glucoside, myricetin–3–O–β– glucoside, querection–3–O–rutinoside (Rutin). All compounds were identified by different spectroscopic analyses (UV, (1)H–NMR, (13)C–NMR) and Mass Spectrometry (MS). Shaheed Beheshti University of Medical Sciences 2014 /pmc/articles/PMC4177630/ /pubmed/25276210 Text en © 2014 by School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Rashed, Khaled
Butnariu, Monica
Antimicrobial and Antioxidant Activities of Bauhinia racemosa Lam. and Chemical Content
title Antimicrobial and Antioxidant Activities of Bauhinia racemosa Lam. and Chemical Content
title_full Antimicrobial and Antioxidant Activities of Bauhinia racemosa Lam. and Chemical Content
title_fullStr Antimicrobial and Antioxidant Activities of Bauhinia racemosa Lam. and Chemical Content
title_full_unstemmed Antimicrobial and Antioxidant Activities of Bauhinia racemosa Lam. and Chemical Content
title_short Antimicrobial and Antioxidant Activities of Bauhinia racemosa Lam. and Chemical Content
title_sort antimicrobial and antioxidant activities of bauhinia racemosa lam. and chemical content
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177630/
https://www.ncbi.nlm.nih.gov/pubmed/25276210
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