Clarithromycin Dissolution Enhancement by Preparation of Aqueous Nanosuspensions Using Sonoprecipitation Technique

Clarithromycin (CLM) is a member of macrolide family with broad spectrum antibiotic activity. It is practically insoluble in water and its poor solubility is pH dependent. In this study, series of nanosuspensions containing CLM and stabilizer such as HPMC, NaCMC, polysorbate 80, poloxamer 188 and po...

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Detalles Bibliográficos
Autores principales: Esfandi, Es ׳hagh, Ramezani, Vahid, Vatanara, Alireza, Rouholamini Najafabadi, Abdolhossein, Hadipour Moghaddam, Seyyed Pouya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177641/
https://www.ncbi.nlm.nih.gov/pubmed/25276181

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