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A Bayesian Framework to Identify Methylcytosines from High-Throughput Bisulfite Sequencing Data

High-throughput bisulfite sequencing technologies have provided a comprehensive and well-fitted way to investigate DNA methylation at single-base resolution. However, there are substantial bioinformatic challenges to distinguish precisely methylcytosines from unconverted cytosines based on bisulfite...

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Detalles Bibliográficos
Autores principales:	Xie, Qing, Liu, Qi, Mao, Fengbiao, Cai, Wanshi, Wu, Honghu, You, Mingcong, Wang, Zhen, Chen, Bingyu, Sun, Zhong Sheng, Wu, Jinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177668/ https://www.ncbi.nlm.nih.gov/pubmed/25255082 http://dx.doi.org/10.1371/journal.pcbi.1003853

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