Extravasation into brain and subsequent spread beyond the ischemic core of a magnetic resonance contrast agent following a step-down infusion protocol in acute cerebral ischemia

BACKGROUND: Limiting expansion of the ischemic core lesion by reinstating blood flow and protecting the penumbral cells is a priority in acute stroke treatment. However, at present, methods are not available for effective drug delivery to the ischemic penumbra. To address these issues this study com...

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Detalles Bibliográficos
Autores principales: Nagaraja, Tavarekere N, Keenan, Kelly A, Aryal, Madhava P, Ewing, James R, Gopinath, Saarang, Nadig, Varun S, Shashikumar, Sukruth, Knight, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177725/
https://www.ncbi.nlm.nih.gov/pubmed/25276343
http://dx.doi.org/10.1186/2045-8118-11-21

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