Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescence

There are two major pathways leading to induction of NF-κB subunits. The classical (or canonical) pathway typically leads to the induction of RelA or c-Rel containing complexes, and involves the degradation of IκBα in a manner dependent on IκB kinase (IKK) β and the IKK regulatory subunit NEMO. The...

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Detalles Bibliográficos
Autores principales: Iannetti, Alessio, Ledoux, Adeline C., Tudhope, Susan J., Sellier, Hélène, Zhao, Bo, Mowla, Sophia, Moore, Adam, Hummerich, Holger, Gewurz, Benjamin E., Cockell, Simon J., Jat, Parmjit S., Willmore, Elaine, Perkins, Neil D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177746/
https://www.ncbi.nlm.nih.gov/pubmed/25255445
http://dx.doi.org/10.1371/journal.pgen.1004642

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