Detection of enterovirus 68 in serum from pediatric patients with pneumonia and their clinical outcomes

Enterovirus 68 (EV68) infection occasionally manifests with fatal outcomes. However, detection of EV68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens...

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Detalles Bibliográficos
Autores principales: Imamura, Tadatsugu, Suzuki, Akira, Lupisan, Socorro, Kamigaki, Taro, Okamoto, Michiko, Roy, Chandra Nath, Olveda, Remigio, Oshitani, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Short Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177794/
https://www.ncbi.nlm.nih.gov/pubmed/24209770
http://dx.doi.org/10.1111/irv.12206
Descripción
Sumario:Enterovirus 68 (EV68) infection occasionally manifests with fatal outcomes. However, detection of EV68 in serum and its clinical outcomes are yet to be determined. In this study, we retrospectively tested stored serum samples collected from pediatric pneumonia patients whose nasopharyngeal specimens were positive for EV68. Of total 28 nasopharyngeal sample-positive patients, EV68 was detected in serum samples among 12 (43%) patients aged between 1 and 4 years. Our results suggest that EV68 can cause viremia by which the virus may exhibit systemic manifestations.

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