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Muscle Atrophy in Response to Cytotoxic Chemotherapy Is Dependent on Intact Glucocorticoid Signaling in Skeletal Muscle
Cancer cachexia is a syndrome of weight loss that results from the selective depletion of skeletal muscle mass and contributes significantly to cancer morbidity and mortality. The driver of skeletal muscle atrophy in cancer cachexia is systemic inflammation arising from both the cancer and cancer tr...
Autores principales: | Braun, Theodore P., Szumowski, Marek, Levasseur, Peter R., Grossberg, Aaron J., Zhu, XinXia, Agarwal, Anupriya, Marks, Daniel L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177815/ https://www.ncbi.nlm.nih.gov/pubmed/25254959 http://dx.doi.org/10.1371/journal.pone.0106489 |
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