Cargando…
Hematopoietic but Not Endothelial Cell MyD88 Contributes to Host Defense during Gram-negative Pneumonia Derived Sepsis
Klebsiella pneumoniae is an important cause of sepsis. The common Toll-like receptor adapter myeloid differentiation primary response gene (MyD)88 is crucial for host defense against Klebsiella. Here we investigated the role of MyD88 in myeloid and endothelial cells during Klebsiella pneumosepsis. M...
Autores principales: | van Lieshout, Miriam H. P., Anas, Adam A., Florquin, Sandrine, Hou, Baidong, van't Veer, Cornelis, de Vos, Alex F., van der Poll, Tom |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177915/ https://www.ncbi.nlm.nih.gov/pubmed/25254554 http://dx.doi.org/10.1371/journal.ppat.1004368 |
Ejemplares similares
-
The Polysaccharide Capsule of Streptococcus pneumonia Partially Impedes MyD88-Mediated Immunity during Pneumonia in Mice
por: de Vos, Alex F., et al.
Publicado: (2015) -
MyD88 Dependent Signaling Contributes to Protective Host Defense against Burkholderia pseudomallei
por: Wiersinga, W. Joost, et al.
Publicado: (2008) -
Bradykinin receptor deficiency or antagonism do not impact the host response during gram-negative pneumonia-derived sepsis
por: Ding, Chao, et al.
Publicado: (2019) -
Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia
por: Hommes, Tijmen J., et al.
Publicado: (2015) -
Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis
por: Achouiti, Ahmed, et al.
Publicado: (2012)