LD-Aminopterin in the Canine Homologue of Human Atopic Dermatitis: A Randomized, Controlled Trial Reveals Dosing Factors Affecting Optimal Therapy

BACKGROUND: Options are limited for patients with atopic dermatitis (AD) who do not respond to topical treatments. Antifolate therapy with systemic methotrexate improves the disease, but is associated with adverse effects. The investigational antifolate LD-aminopterin may offer improved safety. It i...

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Detalles Bibliográficos
Autores principales: Zebala, John A., Mundell, Alan, Messinger, Linda, Griffin, Craig E., Schuler, Aaron D., Kahn, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177985/
https://www.ncbi.nlm.nih.gov/pubmed/25255447
http://dx.doi.org/10.1371/journal.pone.0108303

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