Myeloid Derived Hypoxia Inducible Factor 1-alpha Is Required for Protection against Pulmonary Aspergillus fumigatus Infection

Hypoxia inducible factor 1α (HIF1α) is the mammalian transcriptional factor that controls metabolism, survival, and innate immunity in response to inflammation and low oxygen. Previous work established that generation of hypoxic microenvironments occurs within the lung during infection with the huma...

Descripción completa

Detalles Bibliográficos
Autores principales: Shepardson, Kelly M., Jhingran, Anupam, Caffrey, Alayna, Obar, Joshua J., Suratt, Benjamin T., Berwin, Brent L., Hohl, Tobias M., Cramer, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177996/
https://www.ncbi.nlm.nih.gov/pubmed/25255025
http://dx.doi.org/10.1371/journal.ppat.1004378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177996/
https://www.ncbi.nlm.nih.gov/pubmed/25255025
http://dx.doi.org/10.1371/journal.ppat.1004378

Ejemplares similares