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Reactive Oxygen Species Regulate Caspase-11 Expression and Activation of the Non-canonical NLRP3 Inflammasome during Enteric Pathogen Infection
Enteropathogenic and enterohemorrhagic bacterial infections in humans are a severe cause of morbidity and mortality. Although NOD-like receptors (NLRs) NOD2 and NLRP3 have important roles in the generation of protective immune responses to enteric pathogens, whether there is crosstalk among NLRs to...
Autores principales: | Lupfer, Christopher R., Anand, Paras K., Liu, Zhiping, Stokes, Kate L., Vogel, Peter, Lamkanfi, Mohamed, Kanneganti, Thirumala-Devi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178001/ https://www.ncbi.nlm.nih.gov/pubmed/25254654 http://dx.doi.org/10.1371/journal.ppat.1004410 |
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