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Characterizing Protein Interactions Employing a Genome-Wide siRNA Cellular Phenotyping Screen
Characterizing the activating and inhibiting effect of protein-protein interactions (PPI) is fundamental to gain insight into the complex signaling system of a human cell. A plethora of methods has been suggested to infer PPI from data on a large scale, but none of them is able to characterize the e...
Autores principales: | Suratanee, Apichat, Schaefer, Martin H., Betts, Matthew J., Soons, Zita, Mannsperger, Heiko, Harder, Nathalie, Oswald, Marcus, Gipp, Markus, Ramminger, Ellen, Marcus, Guillermo, Männer, Reinhard, Rohr, Karl, Wanker, Erich, Russell, Robert B., Andrade-Navarro, Miguel A., Eils, Roland, König, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178005/ https://www.ncbi.nlm.nih.gov/pubmed/25255318 http://dx.doi.org/10.1371/journal.pcbi.1003814 |
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