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Flavonoid Fraction of Bergamot Juice Reduces LPS-Induced Inflammatory Response through SIRT1-Mediated NF-κB Inhibition in THP-1 Monocytes
Plant polyphenols exert anti-inflammatory activity through both anti-oxidant effects and modulation of pivotal pro-inflammatory genes. Recently, Citrus bergamia has been studied as a natural source of bioactive molecules with antioxidant activity, but few studies have focused on molecular mechanisms...
Autores principales: | Risitano, Roberto, Currò, Monica, Cirmi, Santa, Ferlazzo, Nadia, Campiglia, Pietro, Caccamo, Daniela, Ientile, Riccardo, Navarra, Michele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178028/ https://www.ncbi.nlm.nih.gov/pubmed/25260046 http://dx.doi.org/10.1371/journal.pone.0107431 |
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