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IGF-IR Mediated Mammary Tumorigenesis Is Enhanced during Pubertal Development

Although breast cancer typically develops in women over the age of 40, it remains unclear when breast cancer initiating events occur or whether the mammary gland is particularly susceptible to oncogenic transformation at a particular developmental stage. Using MTB-IGFIR transgenic mice that overexpr...

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Detalles Bibliográficos
Autores principales:	Jones, Robert A., Watson, Katrina L., Campbell, Craig I., Moorehead, Roger A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178186/ https://www.ncbi.nlm.nih.gov/pubmed/25259518 http://dx.doi.org/10.1371/journal.pone.0108781

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