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RIG-I Self-Oligomerization Is Either Dispensable or Very Transient for Signal Transduction
Effective host defence against viruses depends on the rapid triggering of innate immunity through the induction of a type I interferon (IFN) response. To this end, microbe-associated molecular patterns are detected by dedicated receptors. Among them, the RIG-I-like receptors RIG-I and MDA5 activate...
Autores principales: | Louber, Jade, Kowalinski, Eva, Bloyet, Louis-Marie, Brunel, Joanna, Cusack, Stephen, Gerlier, Denis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178188/ https://www.ncbi.nlm.nih.gov/pubmed/25259935 http://dx.doi.org/10.1371/journal.pone.0108770 |
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