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Metabolic changes in cancer cells upon suppression of MYC

BACKGROUND: Cancer cells engage in aerobic glycolysis and glutaminolysis to fulfill their biosynthetic and energetic demands in part by activating MYC. Previous reports have characterized metabolic changes in proliferating cells upon MYC loss or gain of function. However, metabolic differences betwe...

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Detalles Bibliográficos
Autores principales:	Anso, Elena, Mullen, Andrew R, Felsher, Dean W, Matés, José M, DeBerardinis, Ralph J, Chandel, Navdeep S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Rapid Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178210/ https://www.ncbi.nlm.nih.gov/pubmed/24280108 http://dx.doi.org/10.1186/2049-3002-1-7

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