Preterm delivery and low maternal serum cholesterol level: Any correlation?

BACKGROUND: The study assessed whether low maternal serum cholesterol during early pregnancy is associated with preterm delivery. PATIENTS AND METHODS: It was a prospective observational cohort study involving pregnant women at gestational age of 14-20 weeks over a period of 12 months. Blood samples...

Descripción completa

Detalles Bibliográficos
Autores principales: Oluwole, Ayodeji A., Adegbesan-Omilabu, Maymunah A., Okunade, Kehinde S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178338/
https://www.ncbi.nlm.nih.gov/pubmed/25298606
http://dx.doi.org/10.4103/0300-1652.140381
Descripción
Sumario:BACKGROUND: The study assessed whether low maternal serum cholesterol during early pregnancy is associated with preterm delivery. PATIENTS AND METHODS: It was a prospective observational cohort study involving pregnant women at gestational age of 14-20 weeks over a period of 12 months. Blood samples were obtained to measure total serum cholesterol concentrations and the sera were then analysed enzymatically by the cholesterol oxidase: p-aminophenazone (CHOD PAP) method. RESULTS: The study showed an incidence of 5.0% for preterm delivery in the low risk study patients. Preterm birth was 4.83-times more common with low total maternal cholesterol than with midrange total cholesterol (11.8% versus 2.2%, P = 0.024). CONCLUSION: Low maternal serum cholesterol (hypocholesterolaemia) is associated with preterm delivery. Optimal maternal serum cholesterol during pregnancy may have merit, therefore pregnant women should be encouraged to follow a healthy, balanced diet.

Ejemplares similares