Mutations of Novel Influenza A(H10N8) Virus in Chicken Eggs and MDCK Cells

The recent emergence of human infection with influenza A(H10N8) virus is an urgent public health concern. Genomic analysis showed that the virus was conserved in chicken eggs but presented substantial adaptive mutations in MDCK cells. Our results provide additional evidence for the avian origin of t...

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Detalles Bibliográficos
Autores principales: Yang, Jian, Zhang, Ting, Guo, Li, Hu, Yongfeng, Li, Jinlin, Su, Haoxiang, Xiao, Yan, Ren, Xianwen, Dong, Jie, Sun, Lilian, Li, Li, Yang, Fan, Wang, Jianwei, Yuan, Hui, Jin, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2014
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178415/
https://www.ncbi.nlm.nih.gov/pubmed/25148105
http://dx.doi.org/10.3201/eid2009.140257
Descripción
Sumario:The recent emergence of human infection with influenza A(H10N8) virus is an urgent public health concern. Genomic analysis showed that the virus was conserved in chicken eggs but presented substantial adaptive mutations in MDCK cells. Our results provide additional evidence for the avian origin of this influenza virus.

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