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Circulating Type-1 Anti-Tumor CD4(+) T Cells are Preferentially Pro-Apoptotic in Cancer Patients

Cancer patients frequently exhibit a deficiency in Type-1 (but not Type-2 or regulatory) CD4(+) T cell responses against tumor-associated antigens (TAA), which may limit protection against disease progression or responsiveness to immunotherapy in these individuals. Since such deficiency was acutely...

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Detalles Bibliográficos
Autores principales:	Wesa, Amy K., Mandic, Maja, Taylor, Jennifer L., Moschos, Stergios, Kirkwood, John M., Kwok, William W., Finke, James Harold, Storkus, Walter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178427/ https://www.ncbi.nlm.nih.gov/pubmed/25325015 http://dx.doi.org/10.3389/fonc.2014.00266

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