Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II

In mitosis, the Greatwall kinase (called microtubule-associated serine/threonine kinase like [Mastl] in mammals) is essential for prometaphase entry or progression by suppressing protein phosphatase 2A (PP2A) activity. PP2A suppression in turn leads to high levels of Cdk1 substrate phosphorylation....

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Detalles Bibliográficos
Autores principales: Adhikari, Deepak, Diril, M. Kasim, Busayavalasa, Kiran, Risal, Sanjiv, Nakagawa, Shoma, Lindkvist, Rebecca, Shen, Yan, Coppola, Vincenzo, Tessarollo, Lino, Kudo, Nobuaki R., Kaldis, Philipp, Liu, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178961/
https://www.ncbi.nlm.nih.gov/pubmed/25246615
http://dx.doi.org/10.1083/jcb.201406033

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