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Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1
DNA double-strand breaks (DSBs) are repaired by nonhomologous end joining (NHEJ) or homologous recombination (HR). The C terminal binding protein–interacting protein (CtIP) is phosphorylated in G2 by cyclin-dependent kinases to initiate resection and promote HR. CtIP also exerts functions during NHE...
Autores principales: | Barton, Olivia, Naumann, Steffen C., Diemer-Biehs, Ronja, Künzel, Julia, Steinlage, Monika, Conrad, Sandro, Makharashvili, Nodar, Wang, Jiadong, Feng, Lin, Lopez, Bernard S., Paull, Tanya T., Chen, Junjie, Jeggo, Penny A., Löbrich, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178966/ https://www.ncbi.nlm.nih.gov/pubmed/25267294 http://dx.doi.org/10.1083/jcb.201401146 |
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