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Nitrite Anion Therapy Protects Against Chronic Ischemic Tissue Injury in db/db Diabetic Mice in a NO/VEGF-Dependent Manner

Nitrite anion has been demonstrated to be a prodrug of nitric oxide (NO) with positive effects on tissue ischemia/reperfusion injury, cytoprotection, and vasodilation. However, effects of nitrite anion therapy for ischemic tissue vascular remodeling during diabetes remain unknown. We examined whethe...

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Detalles Bibliográficos
Autores principales: Bir, Shyamal C., Pattillo, Christopher B., Pardue, Sibile, Kolluru, Gopi K., Shen, Xinggui, Giordano, Tony, Kevil, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179307/
https://www.ncbi.nlm.nih.gov/pubmed/24009258
http://dx.doi.org/10.2337/db13-0890