Cargando…

Clinical potential of naloxegol in the management of opioid-induced bowel dysfunction

Opioid-induced bowel dysfunction (OIBD) is a burdensome condition which limits the therapeutic benefit of analgesia. It affects the entire gastrointestinal tract, predominantly by activating opioid receptors in the enteric nervous system, resulting in a wide range of symptoms, such as reflux, bloati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poulsen, Jakob Lykke, Brock, Christina, Olesen, Anne Estrup, Nilsson, Matias, Drewes, Asbjørn Mohr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179399/ https://www.ncbi.nlm.nih.gov/pubmed/25278772 http://dx.doi.org/10.2147/CEG.S52097

Ejemplares similares

Sensitivity of quantitative sensory models to morphine analgesia in humans
por: Olesen, Anne Estrup, et al.
Publicado: (2014)

Effects of Naloxegol on Gastrointestinal Transit and Colonic Fecal Volume in Healthy Participants Receiving Oxycodone
por: Olesen, Anne E, et al.
Publicado: (2019)

The Impact of Opioid Treatment on Regional Gastrointestinal Transit
por: Poulsen, Jakob L, et al.
Publicado: (2016)

Prediction of opioid dose in cancer pain patients using genetic profiling: not yet an option with support vector machine learning
por: Olesen, Anne Estrup, et al.
Publicado: (2018)

Pathophysiology and management of diabetic gastroenteropathy
por: Meldgaard, Theresa, et al.
Publicado: (2019)

Study protocol for a randomised, double-blinded, placebo-controlled, clinical trial of S-ketamine for pain treatment in patients with chronic pancreatitis (RESET trial)
por: Juel, Jacob, et al.
Publicado: (2015)

The effect of duloxetine on mechanistic pain profiles, cognitive factors and clinical pain in patients with painful knee osteoarthritis—A randomized, double‐blind, placebo‐controlled, crossover study
por: Petersen, Kristian Kjær‐Staal, et al.
Publicado: (2022)

Gender, variation in opioid receptor genes and sensitivity to experimental pain
por: Sato, Hiroe, et al.
Publicado: (2013)

A mechanism-based proof of concept study on the effects of duloxetine in patients with painful knee osteoarthritis
por: Ammitzbøll, Nadia, et al.
Publicado: (2021)

Clinical utility of naloxegol in the treatment of opioid-induced constipation
por: Bruner, Heather C, et al.
Publicado: (2015)

Effect of Naloxegol on Opioid-Induced Esophageal Motility Disorder
por: Ulteig, Crista, et al.
Publicado: (2022)

Opioid-Induced Constipation and Bowel Dysfunction: A Clinical Guideline
por: Müller-Lissner, Stefan, et al.
Publicado: (2017)

Cingulate metabolites during pain and morphine treatment as assessed by magnetic resonance spectroscopy
por: Hansen, Tine Maria, et al.
Publicado: (2014)

The Incidence of Sexual Dysfunction in Patients With Irritable Bowel Syndrome
por: Sørensen, Jeanette, et al.
Publicado: (2019)

Naloxegol: First oral peripherally acting mu opioid receptor antagonists for opioid-induced constipation
por: Anantharamu, Tejus, et al.
Publicado: (2015)

Impact of Treatment with Naloxegol for Opioid-Induced Constipation on Patients’ Health State Utility
por: Lawson, Richard, et al.
Publicado: (2016)

Effectiveness of naloxegol in patients with cancer pain suffering from opioid-induced constipation
por: Lemaire, Antoine, et al.
Publicado: (2021)

Evaluating the Safety and Efficacy of Naloxegol in Critically Ill Opioid-Induced Constipation Patients
por: Rizwan, M. Zeeshan, et al.
Publicado: (2023)

Regional gastrointestinal transit times in patients with chronic pancreatitis
por: Larsen, Isabelle M., et al.
Publicado: (2022)

Naloxegol in opioid-induced constipation: a new paradigm in the treatment of a common problem
por: Yoon, Stephanie C, et al.
Publicado: (2017)

Correction to: Effectiveness of naloxegol in patients with cancer pain suffering from opioid‑induced constipation
por: Lemaire, Antoine, et al.
Publicado: (2021)

Pharmacologic Profile of Naloxegol, a Peripherally Acting µ-Opioid Receptor Antagonist, for the Treatment of Opioid-Induced Constipation
por: Floettmann, Eike, et al.
Publicado: (2017)

Dietary Intervention Improves Gastrointestinal Symptoms after Treatment of Cancer in the Pelvic Organs
por: Borre, Mette, et al.
Publicado: (2023)

Population Exposure‐Response Modeling of Naloxegol in Patients With Noncancer‐Related Pain and Opioid‐Induced Constipation
por: Al‐Huniti, N, et al.
Publicado: (2016)

Diabetic Enteropathy: From Molecule to Mechanism-Based Treatment
por: Meldgaard, Theresa, et al.
Publicado: (2018)

Naloxegol and Postoperative Urinary Retention: A Randomized Trial
por: Turan, Alparslan, et al.
Publicado: (2022)

The Pain System in Oesophageal Disorders: Mechanisms, Clinical Characteristics, and Treatment
por: Lottrup, Christian, et al.
Publicado: (2011)

Assessment of visceral pain with special reference to chronic pancreatitis
por: Kuhlmann, Louise, et al.
Publicado: (2022)

Study protocol for a randomised double-blinded, sham-controlled, prospective, cross-over clinical trial of vagal neuromodulation for pain treatment in patients with chronic pancreatitis
por: Muthulingam, Janusiya Anajan, et al.
Publicado: (2019)

Cervical transcutaneous vagal neuromodulation in chronic pancreatitis patients with chronic pain: A randomised sham controlled clinical trial
por: Muthulingam, Janusiya Anajan, et al.
Publicado: (2021)

Population Exposure‐Response Modeling Supported Selection of Naloxegol Doses in Phase III Studies in Patients With Opioid‐Induced Constipation
por: Al‐Huniti, Nidal, et al.
Publicado: (2017)

Naloxegol to Prevent Constipation in ICU Adults Receiving Opioids: A Randomized Double-Blind Placebo-Controlled Pilot Trial
por: Duprey, Matthew S., et al.
Publicado: (2022)

Simulation and Prediction of the Drug‐Drug Interaction Potential of Naloxegol by Physiologically Based Pharmacokinetic Modeling
por: Zhou, D, et al.
Publicado: (2016)

Improved Process for the Preparation of Naloxegol Oxalate, an Opiod Receptor Antagonist
por: Velugula, Siva Rama Kasibabu, et al.
Publicado: (2023)

Colorectal Transit and Volume During Treatment With Prolonged-release Oxycodone/Naloxone Versus Oxycodone Plus Macrogol 3350
por: Poulsen, Jakob L, et al.
Publicado: (2018)

Acute physiological and electrical accentuation of vagal tone has no effect on pain or gastrointestinal motility in chronic pancreatitis
por: Juel, Jacob, et al.
Publicado: (2017)

A Prospective, Real-World, Multinational Study of Naloxegol for Patients with Cancer Pain Diagnosed with Opioid-Induced Constipation—The NACASY Study
por: Davies, Andrew, et al.
Publicado: (2022)

Naloxegol hydrogen oxalate displaying a hydrogen-bonded layer structure
por: Gelbrich, Thomas, et al.
Publicado: (2018)

Can Naloxegol Therapy Improve Quality of Life in Patients with Advanced Cancer?
por: Ostan, Rita, et al.
Publicado: (2021)

Palpebral Fissure Response to Phenylephrine Indicates Autonomic Dysfunction in Patients With Type 1 Diabetes and Polyneuropathy
por: Nielsen, Thomas Arendt, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_djit4ruivuutiqq2kqhq4qh5p0