Cargando…

Collaborative approaches for Target ID in neglected diseases: identifying new antimalarial targets

Detalles Bibliográficos
Autores principales:	Lafuente, Maria Jose, Guidelli-Disse, Sonja, Selenski, Carolyn, Lelievre, Joel, Willson, Timothy, Gamo, Francisco Javier, Drewes, Gerard, Vandal, Omar, Ballell-Pages, Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179400/ http://dx.doi.org/10.1186/1475-2875-13-S1-P54

Ejemplares similares

Identification of Plasmodium PI4 kinase as target of MMV390048 by chemoproteomics
por: Ghidelli-Disse, Sonja, et al.
Publicado: (2014)

Identification of KasA as the cellular target of an anti-tubercular scaffold
por: Abrahams, Katherine A., et al.
Publicado: (2016)

Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug
por: da Cruz, Filipa P., et al.
Publicado: (2012)

Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure–Activity Relationship and Target Identification Studies
por: Wilson, Colin R., et al.
Publicado: (2017)

Discovering antimalarials with a differential mode of action
por: Sanz, Laura, et al.
Publicado: (2014)

Prioritization of Molecular Targets for Antimalarial Drug Discovery
por: Forte, Barbara, et al.
Publicado: (2021)

Antimalarial Drug Resistance and Novel Targets for Antimalarial Drug Discovery
por: Shibeshi, Melkamu Adigo, et al.
Publicado: (2020)

A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue
por: Sonoiki, Ebere, et al.
Publicado: (2017)

Phenotypic Screens, Chemical Genomics, and Antimalarial Lead Discovery
por: Garcia-Bustos, Jose F., et al.
Publicado: (2011)

Design and tests of prospective property predictions for novel antimalarial 2-aminopropylaminoquinolones
por: Clark, Robert D., et al.
Publicado: (2020)

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183
por: de Vries, Laura E., et al.
Publicado: (2022)

Machine learning-based phenotypic imaging to characterise the targetable biology of Plasmodium falciparum male gametocytes for the development of transmission-blocking antimalarials
por: Tsebriy, Oleksiy, et al.
Publicado: (2023)

Pyrazoleamide compounds are potent antimalarials that target Na(+) homeostasis in intraerythrocytic Plasmodium falciparum
por: Vaidya, Akhil B., et al.
Publicado: (2014)

The multi-target aspect of an MmpL3 inhibitor: The BM212 series of compounds bind EthR2, a transcriptional regulator of ethionamide activation
por: Moorey, Alice R., et al.
Publicado: (2021)

How do antimalarial drugs reach their intracellular targets?
por: Basore, Katherine, et al.
Publicado: (2015)

Expanding the antimalarial toolkit: Targeting host–parasite interactions
por: Langhorne, Jean, et al.
Publicado: (2016)

An ImmunoPEGliposome for Targeted Antimalarial Combination Therapy at the Nanoscale
por: Biosca, Arnau, et al.
Publicado: (2019)

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis
por: Edwards, Rachel L., et al.
Publicado: (2017)

Validation of Plasmodium falciparum deoxyhypusine synthase as an antimalarial target
por: Aroonsri, Aiyada, et al.
Publicado: (2019)

Driving antimalarial design through understanding of target mechanism
por: Calic, Petar P. S., et al.
Publicado: (2020)

Targeting Host Glycolysis as a Strategy for Antimalarial Development
por: Jezewski, Andrew J., et al.
Publicado: (2021)

Design, synthesis, and biological evaluation of multiple targeting antimalarials
por: Yang, Yiqing, et al.
Publicado: (2021)

Plasmodium falciparum Nicotinamidase as A Novel Antimalarial Target
por: Donu, Dickson, et al.
Publicado: (2022)

Current and emerging target identification methods for novel antimalarials
por: Challis, Matthew P., et al.
Publicado: (2022)

Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach
por: Mugumbate, Grace, et al.
Publicado: (2017)

OrbId: Origin-based identification of microRNA targets
por: Filshtein, Teresa J., et al.
Publicado: (2012)

Isoxazolopyrimidine-Based Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Antimalarial Activity
por: Kokkonda, Sreekanth, et al.
Publicado: (2018)

Basigin is a druggable target for host-oriented antimalarial interventions
por: Zenonos, Zenon A., et al.
Publicado: (2015)

Muddled mechanisms: recent progress towards antimalarial target identification
por: Edwards, Rachel L., et al.
Publicado: (2016)

Adaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery
por: Marques, Joana, et al.
Publicado: (2017)

Proteases as antimalarial targets: strategies for genetic, chemical, and therapeutic validation
por: Deu, Edgar
Publicado: (2017)

Recent Progress in the Development of New Antimalarial Drugs with Novel Targets
por: Belete, Tafere Mulaw
Publicado: (2020)

The antimalarial resistome – finding new drug targets and their modes of action
por: Carolino, Krypton, et al.
Publicado: (2020)

Heparin-Coated Dendronized Hyperbranched Polymers for Antimalarial Targeted Delivery
por: San Anselmo, María, et al.
Publicado: (2022)

Genetic validation of PfFKBP35 as an antimalarial drug target
por: Thommen, Basil T, et al.
Publicado: (2023)

A Binational Model of Collaboration for Enhancing Cross-border ID Surveillance
por: Ortwine, Kristine, et al.
Publicado: (2013)

Collaborative Health and Enforcement Operations on the Quality of Antimalarials and Antibiotics in Southeast Asia
por: Yong, Yuk Lin, et al.
Publicado: (2015)

In vivo targeted DamID identifies CHD8 genomic targets in fetal mouse brain
por: Wade, A. Ayanna, et al.
Publicado: (2021)

Id2 GABAergic interneurons comprise a neglected fourth major group of cortical inhibitory cells
por: Machold, Robert, et al.
Publicado: (2023)

Study of the efficacy of antimalarial drugs delivered inside targeted immunoliposomal nanovectors
por: Urbán, Patricia, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_72jpnj1shjru18prbnh80snln7