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Cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the USA
OBJECTIVE: To assess the cost-effectiveness of a multifaceted quality improvement programme focused on reducing central line-associated bloodstream infections in intensive care units. DESIGN: Cost-effectiveness analysis using a decision tree model to compare programme to non-programme intensive care...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179409/ https://www.ncbi.nlm.nih.gov/pubmed/25256190 http://dx.doi.org/10.1136/bmjopen-2014-006065 |
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author | Herzer, Kurt R Niessen, Louis Constenla, Dagna O Ward, William J Pronovost, Peter J |
author_facet | Herzer, Kurt R Niessen, Louis Constenla, Dagna O Ward, William J Pronovost, Peter J |
author_sort | Herzer, Kurt R |
collection | PubMed |
description | OBJECTIVE: To assess the cost-effectiveness of a multifaceted quality improvement programme focused on reducing central line-associated bloodstream infections in intensive care units. DESIGN: Cost-effectiveness analysis using a decision tree model to compare programme to non-programme intensive care units. SETTING: USA. POPULATION: Adult patients in the intensive care unit. COSTS: Economic costs of the programme and of central line-associated bloodstream infections were estimated from the perspective of the hospital and presented in 2013 US dollars. MAIN OUTCOME MEASURES: Central line-associated bloodstream infections prevented, deaths averted due to central line-associated bloodstream infections prevented, and incremental cost-effectiveness ratios. Probabilistic sensitivity analysis was performed. RESULTS: Compared with current practice, the programme is strongly dominant and reduces bloodstream infections and deaths at no additional cost. The probabilistic sensitivity analysis showed that there was an almost 80% probability that the programme reduces bloodstream infections and the infections’ economic costs to hospitals. The opportunity cost of a bloodstream infection to a hospital was the most important model parameter in these analyses. CONCLUSIONS: This multifaceted quality improvement programme, as it is currently implemented by hospitals on an increasingly large scale in the USA, likely reduces the economic costs of central line-associated bloodstream infections for US hospitals. Awareness among hospitals about the programme's benefits should enhance implementation. The programme's implementation has the potential to substantially reduce morbidity, mortality and economic costs associated with central line-associated bloodstream infections. |
format | Online Article Text |
id | pubmed-4179409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-41794092014-10-02 Cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the USA Herzer, Kurt R Niessen, Louis Constenla, Dagna O Ward, William J Pronovost, Peter J BMJ Open Intensive Care OBJECTIVE: To assess the cost-effectiveness of a multifaceted quality improvement programme focused on reducing central line-associated bloodstream infections in intensive care units. DESIGN: Cost-effectiveness analysis using a decision tree model to compare programme to non-programme intensive care units. SETTING: USA. POPULATION: Adult patients in the intensive care unit. COSTS: Economic costs of the programme and of central line-associated bloodstream infections were estimated from the perspective of the hospital and presented in 2013 US dollars. MAIN OUTCOME MEASURES: Central line-associated bloodstream infections prevented, deaths averted due to central line-associated bloodstream infections prevented, and incremental cost-effectiveness ratios. Probabilistic sensitivity analysis was performed. RESULTS: Compared with current practice, the programme is strongly dominant and reduces bloodstream infections and deaths at no additional cost. The probabilistic sensitivity analysis showed that there was an almost 80% probability that the programme reduces bloodstream infections and the infections’ economic costs to hospitals. The opportunity cost of a bloodstream infection to a hospital was the most important model parameter in these analyses. CONCLUSIONS: This multifaceted quality improvement programme, as it is currently implemented by hospitals on an increasingly large scale in the USA, likely reduces the economic costs of central line-associated bloodstream infections for US hospitals. Awareness among hospitals about the programme's benefits should enhance implementation. The programme's implementation has the potential to substantially reduce morbidity, mortality and economic costs associated with central line-associated bloodstream infections. BMJ Publishing Group 2014-09-25 /pmc/articles/PMC4179409/ /pubmed/25256190 http://dx.doi.org/10.1136/bmjopen-2014-006065 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Intensive Care Herzer, Kurt R Niessen, Louis Constenla, Dagna O Ward, William J Pronovost, Peter J Cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the USA |
title | Cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the USA |
title_full | Cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the USA |
title_fullStr | Cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the USA |
title_full_unstemmed | Cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the USA |
title_short | Cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the USA |
title_sort | cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the usa |
topic | Intensive Care |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179409/ https://www.ncbi.nlm.nih.gov/pubmed/25256190 http://dx.doi.org/10.1136/bmjopen-2014-006065 |
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