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A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells
The dynamic properties of podosomes, their ability to degrade the underlying matrix and their modulation by Toll-like receptor (TLR) signaling in dendritic cells (DCs) suggests they have an important role in migration. Integrins are thought to participate in formation and dynamics of podosomes but t...
Autores principales: | Gawden-Bone, Christian, West, Michele A., Morrison, Vicky L., Edgar, Alexander J., McMillan, Sarah J., Dill, Brian D., Trost, Matthias, Prescott, Alan, Fagerholm, Susanna C., Watts, Colin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179490/ https://www.ncbi.nlm.nih.gov/pubmed/25086067 http://dx.doi.org/10.1242/jcs.151167 |
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