Cargando…

Targeting IRF5 inhibition in human B cells: identification of new functional roles that implicate IRF5 in systemic lupus erythematosus B-cell pathology

Detalles Bibliográficos
Autores principales:	De, Saurav, Feng, Di, Valdez, Alisha, Pitler, Amy, Barnes, Betsy J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Meeting Abstract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179521/ http://dx.doi.org/10.1186/ar4632

Ejemplares similares

Monoallelic IRF5 deficiency in B cells prevents murine lupus
por: Pellerin, Alex, et al.
Publicado: (2021)

B Cell-Intrinsic Role for IRF5 in TLR9/BCR-Induced Human B Cell Activation, Proliferation, and Plasmablast Differentiation
por: De, Saurav, et al.
Publicado: (2018)

The Systemic Lupus Erythematosus IRF5 Risk Haplotype Is Associated with Systemic Sclerosis
por: Carmona, F. David, et al.
Publicado: (2013)

Specific detection of interferon regulatory factor 5 (IRF5): A case of antibody inequality
por: Li, Dan, et al.
Publicado: (2016)

Detection of neutrophil extracellular traps in patient plasma: method development and validation in systemic lupus erythematosus and healthy donors that carry IRF5 genetic risk
por: Matta, Bharati, et al.
Publicado: (2022)

Effects of IRF5 Lupus Risk Haplotype on Pathways Predicted to Influence B Cell Functions
por: Guthridge, Joel M., et al.
Publicado: (2012)

DNA-binding landscape of IRF3, IRF5 and IRF7 dimers: implications for dimer-specific gene regulation
por: Andrilenas, Kellen K, et al.
Publicado: (2018)

IRF5 expression profiling in SLE patients: new leads to a pathogenic signature?
por: Barnes, BJ, et al.
Publicado: (2012)

Regulation of Age-associated B cells by IRF5 in systemic autoimmunity
por: Manni, Michela, et al.
Publicado: (2018)

Replication of the genetic effects of IFN regulatory factor 5 (IRF5) on systemic lupus erythematosus in a Korean population
por: Shin, Hyoung Doo, et al.
Publicado: (2007)

RNA-Seq for Enrichment and Analysis of IRF5 Transcript Expression in SLE
por: Stone, Rivka C., et al.
Publicado: (2013)

Potential T Cell-Intrinsic Regulatory Roles for IRF5 via Cytokine Modulation in T Helper Subset Differentiation and Function
por: Brune, Zarina, et al.
Publicado: (2020)

IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling
por: Lazear, Helen M., et al.
Publicado: (2013)

IRF4-Dependent and IRF4-Independent Pathways Contribute to DC Dysfunction in Lupus
por: Manni, Michela, et al.
Publicado: (2015)

Correction: IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling
por: Lazear, Helen M., et al.
Publicado: (2013)

IRF5 gene polymorphisms in melanoma
por: Uccellini, Lorenzo, et al.
Publicado: (2012)

Epigenetic Silencing of IRF7 and/or IRF5 in Lung Cancer Cells Leads to Increased Sensitivity to Oncolytic Viruses
por: Li, Qunfang, et al.
Publicado: (2011)

Therapeutic Targeting of IRFs: Pathway-Dependence or Structure-Based?
por: Thompson, Cherrie D., et al.
Publicado: (2018)

The dynamic functions of IRF4 in B cell malignancies
por: Maffei, Rossana, et al.
Publicado: (2022)

Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization
por: Banga, Jaspreet, et al.
Publicado: (2020)

Cis-regulation of IRF5 expression is unable to fully account for systemic lupus erythematosus association: analysis of multiple experiments with lymphoblastoid cell lines
por: Alonso-Perez, Elisa, et al.
Publicado: (2011)

Phosphorylation of Microglial IRF5 and IRF4 by IRAK4 Regulates Inflammatory Responses to Ischemia
por: Ngwa, Conelius, et al.
Publicado: (2021)

TRIpartite Motif 21 (TRIM21) Differentially Regulates the Stability of Interferon Regulatory Factor 5 (IRF5) Isoforms
por: Lazzari, Elisa, et al.
Publicado: (2014)

The gene silencing of IRF5 and BLYSS effectively modulates the outcome of experimental lupus nephritis
por: Guiteras, Jordi, et al.
Publicado: (2021)

IRF5 promotes the proliferation of human thyroid cancer cells
por: Massimino, Michele, et al.
Publicado: (2012)

MAPK phosphatase 5 inhibits IRF3
por: Png, Chin Wen, et al.
Publicado: (2015)

The IRF5 rs2004640 (G/T) polymorphism is not a genetic risk factor for systemic lupus erythematosus in population from south India
por: Devaraju, Panneer, et al.
Publicado: (2018)

Loss of interferon regulatory factor 5 (IRF5) expression in human ductal carcinoma correlates with disease stage and contributes to metastasis
por: Bi, Xiaohui, et al.
Publicado: (2011)

OR7-001 – By chip pyrin binds the IRF2 promoter
por: Wood, G, et al.
Publicado: (2013)

Bach2 overexpression represses Th9 cell differentiation by suppressing IRF4 expression in systemic lupus erythematosus
por: Sheng, Yujun, et al.
Publicado: (2020)

Genetic and chemical inhibition of IRF5 suppresses pre-existing mouse lupus-like disease
por: Ban, Tatsuma, et al.
Publicado: (2021)

Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5′ and 3′ flanking bases, collaborating transcription factors and the chromatin environment in a combinatorial fashion
por: Csumita, Mária, et al.
Publicado: (2020)

IRF5 regulates airway macrophage metabolic responses
por: Albers, G. J., et al.
Publicado: (2021)

TRIM14 expression is regulated by IRF‐1 and IRF‐2
por: Cui, Jingang, et al.
Publicado: (2019)

IRF3 and IRF8 Regulate NF-κB Signaling by Targeting MyD88 in Teleost Fish
por: Yan, Xiaolong, et al.
Publicado: (2020)

Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5
por: Peng, Liang, et al.
Publicado: (2016)

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus
por: Cunninghame Graham, Deborah S., et al.
Publicado: (2011)

Genetic Variation near IRF8 is Associated with Serologic and Cytokine Profiles in Systemic Lupus Erythematosus and Multiple Sclerosis
por: Chrabot, Beverly S., et al.
Publicado: (2013)

IRF4 and IRGs Delineate Clinically Relevant Gene Expression Signatures in Systemic Lupus Erythematosus and Rheumatoid Arthritis
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2019)

IRF4b and IRF8 Negatively Regulate RLR-Mediated NF-κB Signaling by Targeting MITA for Degradation in Teleost Fish
por: Yan, Xiaolong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5fatcmrljhuo5qpbn1mtf0icon