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Crystallographic Evidence of Drastic Conformational Changes in the Active Site of a Flavin-Dependent N-Hydroxylase
[Image: see text] The soil actinomycete Kutzneria sp. 744 produces a class of highly decorated hexadepsipeptides, which represent a new chemical scaffold that has both antimicrobial and antifungal properties. These natural products, known as kutznerides, are created via nonribosomal peptide synthesi...
Autores principales: | Setser, Jeremy W., Heemstra, John R., Walsh, Christopher T., Drennan, Catherine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179590/ https://www.ncbi.nlm.nih.gov/pubmed/25184411 http://dx.doi.org/10.1021/bi500655q |
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