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Changes to signal peptide and the level of transforming growth factor- β1 due to T869C polymorphism of TGF β1 associated with lupus renal fibrosis

Lupus Nephritis (LN) is a serious manifestation of lupus that can lead to End Stage Renal Disease (ESRD). Fibrosis is the main feature of ESRD, and it is likely influenced by Transforming Growth Factor Beta1 (TGFβ1). The T869C gene polymorphism of TGFβ1 is assumed to change the signal peptide, that...

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Detalles Bibliográficos
Autores principales:	Susianti, Hani, Handono, Kusworini, Purnomo, Basuki B, Widodo, Nashi, Gunawan, Atma, Kalim, Handono
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179638/ https://www.ncbi.nlm.nih.gov/pubmed/25279306 http://dx.doi.org/10.1186/2193-1801-3-514

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