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Small GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturation

Macropinosome formation requires the sequential activation of numerous signaling pathways that coordinate the actin-driven formation of plasma membrane protrusions (ruffles) and circular ruffles (macropinocytic cups), followed by the closure of these macropinocytic cups into macropinosomes. In the p...

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Detalles Bibliográficos
Autores principales: Egami, Youhei, Taguchi, Tomohiko, Maekawa, Masashi, Arai, Hiroyuki, Araki, Nobukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179697/
https://www.ncbi.nlm.nih.gov/pubmed/25324782
http://dx.doi.org/10.3389/fphys.2014.00374

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