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Time and dose relationships between schisandrin B- and schisandrae fructus oil-induced hepatotoxicity and the associated elevations in hepatic and serum triglyceride levels in mice
BACKGROUND: Schisandrin B (Sch B), a dibenzocyclooctadiene compound, is isolated from schisandrae fructus (SF). This study was conducted to compare the time- and dose-response between Sch B- and SF oil (SFO)-induced changes in hepatic and serum parameters in mice. METHODS: Institute of Cancer Resear...
Autores principales: | Zhang, Yi, Pan, Si-Yuan, Zhou, Shu-Feng, Wang, Xiao-Yan, Sun, Nan, Zhu, Pei-Li, Chu, Zhu-Sheng, Yu, Zhi-Ling, Ko, Kam-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179757/ https://www.ncbi.nlm.nih.gov/pubmed/25278745 http://dx.doi.org/10.2147/DDDT.S67518 |
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