Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation

Elevated total cholesterol in midlife has been associated with increased risk of dementia in later life. We have previously shown that low-density lipoprotein (LDL) is more oxidized in the plasma of dementia patients, although total cholesterol levels are not different from those of age-matched cont...

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Detalles Bibliográficos
Autores principales: Dias, Irundika H.K., Mistry, Jayna, Fell, Shaun, Reis, Ana, Spickett, Corinne M., Polidori, Maria C., Lip, Gregory Y.H., Griffiths, Helen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180009/
https://www.ncbi.nlm.nih.gov/pubmed/25048970
http://dx.doi.org/10.1016/j.freeradbiomed.2014.07.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180009/
https://www.ncbi.nlm.nih.gov/pubmed/25048970
http://dx.doi.org/10.1016/j.freeradbiomed.2014.07.012

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