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Leptin modulates autophagy in human CD4(+)CD25(−) conventional T cells

OBJECTIVE: In this report we show that the adipocytokine leptin directly modulates autophagy in human CD4(+)CD25(−) conventional (Tconv) T cells. RESULTS: In vitro treatment with recombinant human leptin determined an inhibition of autophagy during T cell receptor (TCR) stimulation, and this phenome...

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Detalles Bibliográficos
Autores principales:	Cassano, Silvana, Pucino, Valentina, La Rocca, Claudia, Procaccini, Claudio, De Rosa, Veronica, Marone, Gianni, Matarese, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	W.B. Saunders 2014
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180014/ https://www.ncbi.nlm.nih.gov/pubmed/25060689 http://dx.doi.org/10.1016/j.metabol.2014.06.010

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