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SMAD4 Regulates Cell Motility through Transcription of N-Cadherin in Human Pancreatic Ductal Epithelium
Expression of the cellular adhesion protein N-cadherin is a critical event during epithelial-mesenchymal transition (EMT). The SMAD4 protein has been identified as a mediator of transforming growth factor-β (TGF-β) superfamily signaling, which regulates EMT, but the mechanisms linking TGF-β signalin...
Autores principales: | Kang, Ya'an, Ling, Jianhua, Suzuki, Rei, Roife, David, Chopin-Laly, Xavier, Truty, Mark J., Chatterjee, Deyali, Wang, Huamin, Thomas, Ryan M., Katz, Matthew H., Chiao, Paul J., Fleming, Jason B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180072/ https://www.ncbi.nlm.nih.gov/pubmed/25264609 http://dx.doi.org/10.1371/journal.pone.0107948 |
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