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Early Cytokine Release in Response to Live Borrelia burgdorferi Sensu Lato Spirochetes Is Largely Complement Independent

AIM: Here we investigated the role of complement activation in phagocytosis and the release of cytokines and chemokines in response to two clinical isolates: Borrelia afzelii K78, which is resistant to complement-mediated lysis, and Borrelia garinii LU59, which is complement-sensitive. METHODS: Borr...

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Detalles Bibliográficos
Autores principales: Sandholm, Kerstin, Henningsson, Anna J., Säve, Susanne, Bergström, Sven, Forsberg, Pia, Jonsson, Nina, Ernerudh, Jan, Ekdahl, Kristina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180076/
https://www.ncbi.nlm.nih.gov/pubmed/25265036
http://dx.doi.org/10.1371/journal.pone.0108013